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The markup of e-cigarettes as high as 200-400% could play a task in the prevalence of vape outlets. The markup for conventional cigarettes is 10-20%, however e-cigarette dispensers, nicotine cartridges, and accessories are as excessive 200-400% markup. A 2015 study found that 5.4% of US center and high school college students were vaping cannabis using e-cigarettes and 18% of vapers had also tried vaping cannabis using their e-cigarette. Some private vaporizer devices can be utilized with cannabis plant materials or a concentrated resin form of cannabis called "wax". E-cigarettes may be altered to use hash oil, wax concentrated with tetrahydrocannabinol (THC), or dried cannabis leaves. E-liquids may be stuffed with substances other than nicotine, thus serving as a strategy to deliver different psychoactive medication, for example THC. Grana R, Benowitz N, Glantz SA (Might 2014). "E-cigarettes: a scientific review". Wang M, Wang JW, Cao SS, Wang HQ, Hu RY (January 2016). "Cigarette Smoking and Electronic Cigarettes Use: A Meta-Analysis". Chatham-Stephens K, Law R, Taylor E, Melstrom P, Bunnell R, Wang B, et al. Singh T, Kennedy S, Marynak K, Persoskie A, Melstrom P, King BA (December 2016). "Characteristics of Electronic Cigarette Use Among Middle and High school Students - United States, 2015". MMWR. Tsai J, Walton K, Coleman BN, Sharapova SR, Johnson SE, Kennedy SM, Caraballo RS (February 2018). "Reasons for Electronic Cigarette Use Among Middle and High school Students - National Youth Tobacco Survey, United States, 2016". MMWR. Drope J, Cahn Z, Kennedy R, Liber AC, Stoklosa M, Henson R, et al. Hoffman AC, Salgado RV, Dresler C, Faller RW, Bartlett C (November 2016). "Flavour preferences in youth versus adults: a review". Delnevo CD, Giovenco DP, Steinberg MB, Villanti AC, Pearson JL, Niaura RS, Abrams DB (May 2016). "Patterns of Electronic Cigarette Use Among Adults within the United States". Glasser AM, Collins L, Pearson JL, Abudayyeh H, Niaura RS, Abrams DB, Villanti AC (February 2017). "Overview of Electronic Nicotine Delivery Systems: A scientific Review".